The preprint study by virology researchers at Austria's Medical University of Innsbruck, which has not been peer-reviewed, went online two days before the FDA expanded the EUA for Paxlovid, though the drug was associated with COVID rebounds even before Fauci's bout.
Citing the FDA's initial authorization of Paxlovid, the researchers searched for "resistant mutants" against the drug's protease inhibitor, nirmatrelvir.
To avoid the perils and regulatory burdens of gain-of-function experiments, they engineered a "chimeric" virus with COVID's main protease and then "applied selective pressure" with nirmatrelvir to induce mutations. The researchers confirmed the effect of the mutants by reintroducing the protease and testing with a cellular assay.
While they identified several mutations in the protease that "confer resistance" to nirmatrelvir, they also discovered that "mutations predicted by our method already exist in SARS-CoV-2 sequence depositions" in databases maintained by the U.S. National Library of Medicine and GISAID global genomic initiative.
Carlos Santana Collapses On Stage During Concert Due To ‘Serious Medical Issue’ | Rant & Rave, Editorials, Beaufort Observer, Op-Ed & Politics | French parliament votes down vaccine passports |
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this at the time that pro-Hamas radicals are rioting around the country
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Pro death roundtable
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political scheme behhind raid on Mar-a-Lago
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Barr had previously said he would jump off a bridge before supporting Trump
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illegal alien "asylum seeker" migrants are a crime wave on both sides of the Atlantic
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only one holdout against acquital
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DEI now includes criminals?
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Biden regime intends to force public school compliance as well as colleges
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clamps down on oil drilling in Alaska
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prosecutors appeal acquittal of member of parliament in lower court for posting Bible verse
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The Missouri Senate approved a constitutional amendment to ban non-U.S. citizens from voting and also ban ranked-choice voting.
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this is the propagandist mindset of MSM today
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same insanity that created Covid
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committee gets enough valid signatures to force vote on removing Oakland, CA's Soros DA
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other pro-terrorist protests in Chicago shout "Death to America" in Farsi
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